Lifeasible Updates Yeast-Based Screening Platform to Accelerate Plant Resistance Gene Discovery

Lifeasible, a biotechnology company specializing in agricultural research, announced an update to its yeast-based high-throughput screening platform to help researchers rapidly identify plant genes that confer resistance to environmental stressors, pests, pathogens, and heavy metals. Plants face increasing challenges from persistent heavy metal contamination in soil, disease attacks, and other environmental stresses, which significantly affect plant growth, yield, and crop quality. Identifying genes associated with resistance is crucial for modern breeding programs, as traditional screening methods are often slow, time-consuming, and have limited throughput, requiring faster and more cost-effective alternatives.

In toxicology and stress response studies, model systems such as yeast provide a viable alternative to animal models, enabling high-throughput gene function analysis at a lower cost. Backed by years of experience in molecular biology, Lifeasible now offers one-stop services for high-throughput resistance gene screening using yeast. Main services include construction of yeast expression libraries, isolation of RNA, construction of cDNA libraries, high-throughput screening for resistance genes, preparation of yeast working solutions, exploration of appropriate adverse conditions, screening of positive yeast clones under adverse conditions, gene identification of yeast positive clones, protein-induced expression and validation, phenotypic validation of yeast, knock-out yeast strain creation and transformation, and complement verification.

Isla, a representative speaker from Lifeasible, commented that the update combines the speed and flexibility of yeast genetics with a robust screening workflow, allowing scientists to explore complex resistance mechanisms more efficiently and unlock new possibilities in plant biotechnology and crop improvement. Over the years, Lifeasible has provided a wide range of services in plant biotechnology, including gene cloning, gene expression, modification, protein-protein or protein-DNA interactions, cell imaging, and phytochemical analysis to meet diversified research needs. For more detailed information about the updated yeast-based high-throughput screening for resistance genes, visit https://www.lifeasible.com/custom-solutions/plant/analytical-services/high-throughput-screening-for-resistance-genes-using-yeast/.