Soligenix Reports Positive Phase 2 Results for Behçet's Disease Treatment
January 16th, 2026 8:21 PM
By: Newsworthy Staff
Soligenix announced positive top-line data from its phase 2 clinical trial evaluating SGX945 for treating aphthous ulcers in Behçet's disease, offering potential new options for this rare inflammatory condition with limited treatments.

Soligenix Inc. has released positive top-line results from its phase 2 clinical trial evaluating SGX945 for the treatment of aphthous ulcers associated with Behçet's disease. The company is reporting results from a phase 2a proof of concept study evaluating its investigational therapy, SGX945 (dusquetide), for the treatment of Behçet's disease, representing a notable step forward in efforts to improve care for patients with this underserved condition.
Behçet's disease is a rare, chronic inflammatory condition that can cause recurrent, painful ulcers, eye inflammation and systemic complications that significantly affect quality of life. The disease is characterized by unpredictable flare-ups and periods of remission, making long-term management particularly challenging. Because available treatments are limited and often inconsistent, clinical trial updates in this disease area carry particular importance. Current treatment strategies for the disease focus on controlling inflammation and suppressing immune activity using corticosteroids, immunosuppressants and biologic agents.
Behçet's disease is classified as a variable vessel vasculitis, meaning it can affect blood vessels of all sizes throughout the body. The positive data from Soligenix's trial suggests potential new therapeutic options for patients who have struggled with the debilitating symptoms of this condition. The latest news and updates relating to SNGX are available in the company's newsroom at https://nnw.fm/SNGX. For more information about the communications platform that distributed this news, please visit https://www.NetworkNewsWire.com. Full terms of use and disclaimers applicable to all content provided by NNW are available at https://www.NetworkNewsWire.com/Disclaimer.
The significance of these results extends beyond the immediate patient population to the broader rare disease research community. Positive outcomes in phase 2 trials for rare inflammatory conditions like Behçet's disease demonstrate the viability of novel therapeutic approaches and encourage further investment in underserved medical areas. The data from this trial could potentially lead to more consistent and effective management strategies for patients who currently face limited treatment options and unpredictable disease progression.
As a rare disease affecting multiple body systems, Behçet's presents unique challenges for both patients and healthcare providers. The unpredictable nature of flare-ups combined with the systemic complications creates a need for treatments that can provide more reliable control of symptoms. The phase 2 results for SGX945 represent progress toward addressing these unmet medical needs and offer hope for improved quality of life for those living with this challenging condition.
Source Statement
This news article relied primarily on a press release disributed by InvestorBrandNetwork (IBN). You can read the source press release here,
