South Fork Instruments Launches Kemtrak UV Spectra for Real-Time Bioprocess Monitoring

South Fork Instruments has announced the availability of the Kemtrak UV Spectra Process Analyzer, a multi-wavelength deep-UV photometer designed for real-time absorbance measurement of proteins, peptides, polypeptides, mRNA/DNA, amino acids, APIs, and process intermediates. The analyzer provides high-resolution continuous absorbance measurement from 190 to 440 nm, supporting applications in chromatography, filtration, biochemical production, and process monitoring. This development is significant because it addresses the increasing demands of modern bioprocessing, where higher concentrations and more complex purification steps require more sophisticated measurement tools.

According to John Daly, Technical Director at South Fork Instruments, bioprocessing teams are working with higher concentrations and more demanding purification steps than ever before. The Kemtrak UV Spectra provides the deep-UV performance, zero-dead-volume measurement, and verification tools needed to generate reliable inline data. Its stability and real-time multi-wavelength capability make it a strong fit for chromatography, filtration, and high-value process streams. The analyzer's advanced features enable more precise monitoring of critical parameters throughout the production process, which is essential for maintaining product quality and consistency in pharmaceutical and biochemical manufacturing.

The Kemtrak UV Spectra offers high-stability optical measurement with up to 10 user-selectable wavelengths, ±0.005 AU photometric resolution, and a 10 Hz sampling frequency for continuous real-time monitoring. To support accurate inline measurement, the system integrates zero-dead-volume hygienic measurement cells available in stainless steel, titanium, Hastelloy, Monel, PTFE, and PPSU, with window options in sapphire and UV-fused silica. Wetted surfaces are available with electropolished finishes down to Ra _ 0.38 μm. These material options ensure compatibility with various process streams and regulatory requirements in pharmaceutical and industrial applications.

Key features of the analyzer include multi-wavelength deep-UV absorbance measurement from 190–440 nm with up to 10 user-selectable wavelengths, high-resolution continuous measurement with ±0.005 AU photometric resolution and fast, 10 Hz sampling, zero-dead-volume hygienic measurement cells in multiple wetted materials for fast response inline monitoring, mercury-free UV-xenon light source with up to two years of continuous operation, and integrated traceable verification with NIST-compliant reference standards and verification port. The mercury-free light source is particularly important as it eliminates environmental and safety concerns associated with traditional mercury lamps while providing extended operational life.

The Kemtrak UV Spectra adds a deep-UV measurement option to South Fork's instrumentation lineup for chromatography, filtration, and real-time process monitoring. This expansion of measurement capabilities allows for more comprehensive process monitoring solutions across various industries. The analyzer's ability to provide real-time data on multiple wavelengths simultaneously enables more sophisticated process control strategies and faster response to process variations. For more information about the analyzer or configuration options, visit www.southforkinst.com. The introduction of this technology represents a significant advancement in process analytical technology for the biopharmaceutical and biochemical industries, where precise measurement and control are critical for product quality and regulatory compliance.