Ventiv Scientific Reports Successful First-in-Human Use of V-PULSE Mechanical Thrombectomy System

Ventiv Scientific today announced the successful completion of its first-in-human clinical cases utilizing the V-PULSE™ Mechanical Thrombectomy System, a novel platform designed to remove blood clots from peripheral vasculature. The system addresses critical challenges in mechanical thrombectomy, a key treatment for conditions such as deep vein thrombosis, acute limb ischemia, and pulmonary embolism.

In the initial procedures, the V-PULSE system demonstrated effective clot removal with immediate visual confirmation of thrombus capture through its integrated filtration technology. Dr. Makmood Razavi of St. Joseph Heart & Vascular Center in Orange, CA, noted, “The V-PULSE system removed significant clot burden and provided immediate visual confirmation of thrombus capture. The device demonstrated excellent control and procedural efficiency.”

Unlike conventional aspiration systems that rely on continuous vacuum, V-PULSE provides real-time control over aspiration force at the catheter tip, allowing physicians to rapidly adjust aspiration to minimize clogging and reduce procedural blood loss. John O'Connor, President of Ventiv Scientific, explained, “Aspiration thrombectomy systems can remove substantial volumes of blood while attempting to extract thrombus. The V-PULSE platform was engineered to provide physicians with procedural control and potentially reduce blood loss while remaining compatible with existing aspiration pumps.”

Peripheral thrombectomy is commonly used in treating deep vein thrombosis, acute limb ischemia, critical limb ischemia, chronic total occlusions, and pulmonary embolism. Effective clot removal is critical, as delayed treatment can lead to serious complications. The V-PULSE system is designed to improve clot extraction performance through a differentiated aspiration-control platform.

Ventiv Scientific's thrombectomy portfolio currently includes the FDA-cleared Control Aspire® Mechanical Thrombectomy System, indicated for peripheral and coronary applications. In addition to V-PULSE, the company is developing next-generation technologies, including a proprietary multi-strut thrombectomy basket retrieval platform currently under investigation. These products have not yet been cleared by the FDA.

For more information, visit Ventiv Scientific.